This game is not intended as a quick lay game. It is a relational/dating game simulating the experiences of a newly developing mutant finding himself with many possible relationship options. Sex comes as a result of navigating interpersonal experiences with the ladies. That this takes time and effort is by intent as the MC does not have mind control or corruption power over the ladies. There is a help menu in game that you can read through that may aid you in determining how to navigate sexual interactions, or as Richard Pryor once stated in a line in a movie (See No Evil, Hear No Evil), "You gotta feel around and see what's happening."
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At the beginning, the question marks next to the options in the sexual action menu indicate that you do not know what a particular lady likes at certain times. As you engage in further encounters with her you may begin to see red and blue hearts on certain options as you get to know her preferences. When you see an option with a red heart it will give greater gains, a blue heart gives negatives as she is tired of that action. These can change during a scene to simulate that the girl wants a different kind of stimulation so you have to keep an eye on them and switch it up sometimes.