Ima throw some guess here since chapter 2 is steadily approaching.
Since chapter 2 is labeled as the Phoenix Saga, going off that... If I were to guess, I think Emma has a decent shot of making a debut, but like mid year. Since she played a role on the Phoenix resurrection in one of the animated show (Although, I know that the dev is building their own stories, with some small correlation from the shows and comics, correct me if I'm wrong. I'm just throwing a huge curveball here).
Storm is confirmed for chapter 2, so I thought about her quirk system and ended up on her possibly to be an "exhibitionist", but not like, in an extreme way. Dev's did wanted some new quirks for future LI. She seems to blush at two instances during the "day 1" event, when she talked about swim suits in the locker room (This could also be a nod to a quirk of her liking when Null calls her a professor? Idk if that's a quirk or not) and when Laura complimented Null muscle/appearance. Probably 20-80 on this one.
Kitty could also show up? Since each chapter goes by seasons, chapter 2 would be a new year and could introduce a new student, which could be Kitty I hope.
Colossus could be a new bro, like Kurt. There's already standing art of the guy. Or maybe he is another professor of sort, and we'll get Scott as a bro instead since he was close with Jean. Since Colossus will eventually appears, maybe his sister, Magik could also appear. It's a long shot.
Antagonist wise, I have no idea for chapter 2 other than the Phoenix herself. Chapter 1 antagonist would probably be that professor guy we met at the prologue, Prof. Farouk. I didn't know about him until I searched him up... Either we'll meet him at Chapter 1 finale or we'll get him later.
My guess for future love interest is a toss up between the female names I mention above. We're getting 2 more aside from Storm so that's hype, I'm breakdancing rn