The point of tags is to let players know what content the game contains. This game contains drugs(in the form of potions), and it also contains mind control content. Since most players avoid games with content they don't like, it's important to include tags for everything the game contains. Some players don't want to play games with mind control content, but are okay with (non-mind-controlling)drugs, or vice versa.
Basically, it's not about the difference between the tags, it's about including every applicable tag. Even if tags have some overlap, it's important to tag the game with everything it contains, so that players aren't surprised with content they may not want to see.