As mentioned in the foreword, this isn't a "defeat the demon king" sort of game. You have what Krowley likes/wants to do (perceive tits), and various methods of getting his or other's dicks wet, with an absolute value of 6% on characters that are unlikely to ever be lewded (that's an approximation, and by god I hope the ones I'm talking about are obvious). If you want engaging plothooks with every update that will leave you breathless and raving about how you can't possibly wait for another update but you can't be bothered to support the dev (very loose interpretation of your words, of course), this isn't that, no.
You seem to be having general issues. I've forgotten what the 'run' key specifically is, but you should be able to directly set him to always run in the settings. Maybe make sure your system is able to run RPGM games in general? No idea what, exactly, you might need to update or check, but the issues you're having sound wild and not directly related to the game in itself. If other games seem to work fine, try deleting your local files for this one or unpacking the new version to a different directory and launch from there?
You need bottles to contain the sperm, which you can grab I think one for free from Krowley's table, and otherwise need to buy from Sebastian or have bottles leftover from used potions. And the orc camp is found to the right/above the bottom-most zone (have to get through there to access it, unless you can Teleport there).
There's a decent amount of order to the chaos.
Nah, just use your noggin for a couple of consecutive seconds when facing a problem. Or, you know, look for the relevant answers and heed them.
Complete his relevant quest. Haven't actually done it myself yet, but it has been implemented according to the changelog, and is a gradual change once that quest is completed (that can be sped up or reversed).