I have a few from the top of my head that, more often than not, makes me drop a game.
-Women wearing high heels.
Not a massive deal breaker, but I'm not a fan of them. The less I see of them, the better.
-"I took a photo of you nude in the shower, now have sex with me"
A.k.a shitty blackmail reasons. It's one thing if you take a photo of someone cheating on their SO, but... oh no, this person was horny and masturbated and I took a photo of it so now said person must have sex with me... I feel as if that's one of the dumbest arguments I've heard.
-"I haven't had sex in so long, oh no, I saw my son's penis, now I must have sex with him".
I... can't begin to describe how much "what" this is for me. Unless it's a post-apocalyptic world with limited means of communication, you can literally just go to a bar, join a dating site or... whatever and get laid like that. But no. Haven't had sex (dead husband, divorced or w/e)... still won't get a new boyfriend/husband. Doesn't matter if it's been several years since the husband died/divorced... nope, dry spell, refuse to find new husband, better suck son's cock.
-Forced NTR.
I hate NTR with a passion. It's happened to me three times. It's not hot. It's a fucking pain. No matter how much I like the game, the instance that happens, I drop it and don't look back.
My biggest (minor) issue is probably this one:
-"I am a strong independent woman that don't need no man... oh no I have had sex once I must now service him".
I'm all for maledom/femsub, but this is one that REALLY doesn't interest me in the least. I'd much rather slowly break down her willpower over the course of multiple interactions and not have her instantly drop down and worship the ground where I walk.