Yeahhh I got a bit carried away because I just really like Cold Rod's TF fetishes,
but now that I think of it their games really do have no persistent effects or TFs.
Although the heroine
does suffer leveling down in the form of transforming into lesser beings,
in Cold Rod's games it is only through the Bad Ends and nowhere else.
Their games don't have status effects either from what I remember.
Thank you again for your requests,
but let's try and stick to games that has as many as possible of the following:
1) persistent status effects and/or transformations
2) levels down the heroine in degrading/humiliating ways, either through, corruption, mana drain, body modification, class changes, descending degress of slavery, player choices being made by a lustful mind, etc.
3) skills/name/items/equipment be replaced by lewd ones
4) dialogues/interactions/sex events that change a lot corresponding to your changed heroine
and all these need to be closely linked to gameplay in exciting ways.
Not just superficious stat sheets, mere numbers on a screen.
We want our magical/fighting skills to be forcefully unlearned and replaced by completely debasing masturbation skills. We want NPCs and surroundings to react to our changed status. We want a hypnosis debuff that force your character to choose the sexual option instead of fighting. We want our lustful, bad girl choices to be punished. We want movement to be overtaken by the game, being led naked on all fours by the leash of the mob who defeated you. We want mid-combat, interactive struggles that might be harder the more curses/statuses you've accumulated.
We want gameplay-augmented deleveling of our heroine.
I think
Ero Dungeons fit the criterias quite well even if they have no actual
sex yet.
Its gamealtering statuses and classchanges are really well made, and it even slowly corrupts your captured party members the longer you delay their rescue. Carefully recommended right now as it is only in its early phase and far from a complete package.