HI!
Yep, usually a sphere means a missing item. The way you know what item is missing depends on your game configuration. Mine is when a scene finish to load, a message prompt in the upper left corner saying "scene loaded", if there any missing mod, it will also prompt the name of the missing mod. You also can see what is missing in the console window or using HS2PNGInfo and see the report.
As the camera go blurry, maybe is because an Deep Of Field (DOF)option is activated. If you can share that scene data we can try to help you.