Some ideas that have popped into my head during vacation and lots of time playing:
Some holidays being marked, like maybe New Years fireworks at central square and lots of people gathered?
More dangerous situations, like if you're walking around half naked, drunk or especially if hammered in the wrong parts of the city, you should be in more danger of getting taken advantage of without having a chance to resist. Unless you have some sober friend or partner nearby. Which brings me to next part; being able to call a friend from the bathroom or similar if in need of help and still not too drunk. Being high should also make more of a difference, and maybe make it more clear what the different drugs do (maybe drug dealer can explain if asking, though may not be completely honest about the cons of said drugs).
NPCs having separate stats for how much they lust the PC and how much they like/love her. Having a high lust low love partner could be an interesting scenario. A low love partner catching you with someone else in an intimate scenario would blame you even if you were a victim, while a high love partner would be more likely to believe you (even if you were willingly cheating on your partner).
Having a boss lusting after you may also make it harder to keep your job unless you give in. While a low lust boss would be harder to seduce so that you actually have to be good at your job and no slacking off.
And some stranger who may be lusting for you but you keep ignoring or telling to piss off may turn into a stalker.
A possibility of someone breaking into your apartment in some areas of the city? Stealing stuff from you like any money you may have hidden in your desk or any drugs you have there? Any stalker you have could just steal underwear or adult toys for instance.
Gambling in this game is a quick way to prosperity, especially if save scumming, maybe if you win a lot in a session make it so that security stop you and kick you out due to suspicion of cheating, and then you're barred from entry for a week or more. Nothing against cheating for easy money, but would make sense if they stopped you, no decent casino would willingly lose that much money to a single person if they suspected foul play. Winning roulette 10x in a row while betting everything you have DOES seem quite suspicious.
When job searching, maybe list the approximately starting salary, so that you don't have to get a job interview first to know what you would earn. Making it easier to compare the different jobs. And maybe a little note about requirements for getting the job. Like for office you obviously need the secretary course and in some cases some experience, but a specialist also need university degree.
Being able to buy a metro week/month pass.
Online shopping, being able to order some (expensive) clothes from abroad for instance, or some random small things. Nothing major that you can't get ahold of in the city. Also, when shopping clothes, being able to see quality before buying and maybe the length of the skirt (long, medium, short, very short) or other small details like that. Would be nice to have it in text and to know if my panties (or lack thereof) would show, or if I would risk an accidental nip slip. But also because I would love some flavour text. The more expensive stores could have more expressive and detailed descriptions, while the markets barely bothers writing anything at all.
(That being said, I haven't played latest update yet due to only having mobile data so waiting until back home to my WiFi for that, so if any of this is already a thing, my mistake. But I think these random ideas, at least most of them, would be more long term ideas. And most importantly, these are just ideas, and may sound better in my head than in text).
Happy New Year, love this game so far