I'd recomend you play Katawa Shoujo if you're into the very retro visual novel genre. First adult game I'd every played, back in 5th grade lol
And yes, there are physically disabled persons as love interests.
Hisao Nakai: The protagonist, with a bad heart disease.
Emi Ibarazaki: The energetic amputee who keeps on running with prosthetic legs
Rin Tezuka: The eccentric artist who keeps on painting despite being a born amputee with no arms
Shizune Hakamichi: Student president council, cannot hear and speak but doesn't let that hold her back
Lilly Satou: Ever graceful and ladylike, she can intricately arrange tea sets despite being born blind
Hanako Ikezawa: Shy girl, gradually recovering and learning to love her physique after almost being burned alive
Kenji: Not a love interest. The only one with mental disabilities. The original right-wing lunatic. But still funny enough for comic relief.
I love this game because the description baits you in with the "disabled girls" kink, but you realize soon enough that each and every one of our protagonists and heroines are defined by their passions and personalities, not their disabilities. The physical scars each one carries soon becomes an afterthought as you become immersed in their day-to-day stories of toiling toward their dreams - dreams no different from other people their age.
I was a depressed little fucker with no friends (having recently transferred schools after getting caught up in too much personal drama at my old one) when this game came out, and boy did I resonate strongly with Rin, especially. It gave me the courage back then to push forward, be more social, figure out what I want to do with my life. This game always holds a special place in my heart
PS: Also, disregard Mariohhhhhh's mean comments. His lack of class reeks like a troll