Don't you heal Alice with simply Antibiotics that you get from the wandering traders group that you encounter randomly sometimes? I'm pretty sure it was that when I played last time. Unless they changed how that plot goes? And also if you did play it all thoroughly and paid attention to the plot, you should be aware that the MC ain't just a regular dude.
I'd be pretty surprised there wouldn't be an harem ending especially if you actually did everything there is to be done, all the girls are aware that you have a relationship with all the others and they all agree to varying degrees with only one that actually has a hard time with it and I wouldn't be surprised if by the time the game is finished (which I feel we are nowhere near that and that's 100% fine) she will have turned around if you do the right stuff.
Damn I don't know what is your requirement for "something happening" because from what I remember the last time I played there is quite a lot of events with twists and turns that happened with both the main story and all the girls relationships. So that statement got me quite confused in fact.