Sorry, I must have remembered wrong or not been evil enough. I've never found anything with Berdita early in Act 1.
OK, I started over and figured this out. In Act 1 when you find the missing boat there are three branches which I say have significant content. It is actually where the game gives you the option to change your alignment.
Good path: go back to college.
Neutral path: go on a demon hunter quest with Isabella.
Evil path: go Bredita's lair for some quests.
I've just played to the point they join back together when you go to the battle at Elvania. So, not sure how it changes the story beyond that.
I find it interesting that you learn many different things about the world on each path. It seems like the dialog when the branches reunite will be different as the character knows different things.