I noticed something about the routes in this game. They seem to be split into 2 groups of 5-6.
The first group is the A-team which includes all the "main" girls, Maya/Josy/Sage/Jill/Bella. This is the A group.
The B-team is what you switch to if you pick the "others" path. While this path has a lot of girls there seem to be 6 "main" girls that could become endgame routes. There is Quinn/Riona/Lily/Nicole/Nora/Zoey. These girls seem the most likely of the "other" girls to become full routes, for reasons as follows.
1. Quiin-- I think everyone has already caught on to Quinn's growing Tsundere feelings for the MC and her large amount of scenes compared to other "side" girls.
2/ Riona-- She showed some clear interest in the MC during the Halloween event( especially when she mentioned she would be hoping the MC might return to being single if you turned down her make-out chance) but the date event during this update has sealed the deal IMO.
3. Lily-- Lily is more of a stretch than the others but she protests a bit too much about not catching feelings for her yet she is rather quick to break her kissing rules and I think the other Hots are onto something when they claim she likes him.
4. Nicole-- Nicole is much easier to confirm as she has shown an increasing amount of affection for the MC over the last few updates and her date makes things rather clear where things are heading.
5. Nora-- We haven't spent as much time with Nora as the others but her date event( specifically her asking the kids questions and other things to weed out dealbreakers) Shows that she is seriously considering the MC as a potentially long-term relationship.
6. Zoey-- Because the childhood friend route is always an option, especially if the MC tells Jacob not to go there.
The A-Team girls also easier to be in a relationship with the MC. (Maya/Josy/Sage/Jill are all classmates and Bella says the rules for librarians like her are laxer than for teachers.)
The B-Team on the other hand has Quinn(drug dealer/ legal and physical danger), Riona(same as Quinn), Lily(stripper and drug distrubuter for strip club/ legal trouble and social stigma against strippers) Nicole(Drug purchaser plus single mom stripper social stigma), and Nora( an actual teacher with the legal liabilities that involves).