I was thinking that if the claims by Unreal are true regarding 5, that you can put your models as they are in the engine, then you could have these models in a real time 3D environment, interesting.
Of course it would not be without a new host of problems, the 3D environment would certainly introduce more variables, aka more ways the game can break, plus it would run on less computers and finally, to use these models as pre-rendered entities as a cost but if you use the actual model in a game is much more expensive to license (one dev mentioned it here time ago).
Still, while I look forward to 3D games, making 3D as 2D like this has its advantages too I think, there is more control over the photography, how the game will present itself, in terms of the way is framed, and how it looks, you don't have to worry about the aliasing on the user's end for one thing.
EDIT: To be clear I wrote this here, because I know Philly actually browses these threads so I'd like to hear from him his opinion on the matter.