Then assign more memory to ren'py.
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I don't think memory is the issue. I have 32GB in my system. Windows error logs this event in its application log though:
Faulting application name: Cockham.exe, version: 0.0.0.0, time stamp: 0x58942445
Faulting module name: swscale-4.dll, version: 4.0.100.0, time stamp: 0x56d002ab
Exception code: 0xc0000005
Fault offset: 0x00015273
Faulting process ID: 0x0x46EC
Faulting application start time: 0x0x1DA2C83259000D5
Faulting application path: C:\Games\Cockham-v0.5.1-pc\lib\windows-i686\Cockham.exe
Faulting module path: C:\Games\Cockham-v0.5.1-pc\lib\windows-i686\swscale-4.dll
Report ID: dc8c2612-ba52-49d5-a6e0-474b67ca1a58
So it looks like the swscale-4.dll is crashing the game for some reason.