Mostly, yes.Are you saying that SHIFT + O doesn't open up the console? In that case, you would need to:
Open CollegeKings2 Folder >renpy > common > open "00console.rpy" in a text file manager like notepad (don't get mixed up with "00console.rpyc"). Hit CTRL + F and search for "config.console". It should take you to a line that says "config.console = False". Change False to True then save the file.
Re-open the game and you should be able to press SHIFT + O to open the console.
For commands, I would have to try it myself since it's been awhile, but I think it's something like "CharacterService.set_relationship(Aubrey, Relationship.GIRLFRIEND)"
Obviously choose whichever character you want and then the relationship status is either FRIEND, FWB, GIRLFRIEND
There are other 'steps' for some if you want to experience the full paths. Some are used as prerequisite steps, but may possibly be looked at again in the future. For example, buying Aubrey flowers, asking her on the date in the Netherlands, and the such.
Other like Chole, don't have a FWB stage. They are either Friend or Girlfriend.
If skipping most of the story is important, wouldn't the Path Builder be easier? Can pick what chapter you start in (CK1 and 2) as well as the friendship status for all characters, and even variables such as fundraising or the president elections.