The game right now has more bugs than before the 1.0 release.
Not to mention the resource management stuff is just too expensive, it's not even worth looking at the conquest 'minigame'.
Conquest levels up you're Laboratory Level, which in turn gives you more money each week. I recommend sending your highest level Bio-soldiers on low level raids with the best equipment, that way they have a much higher survival chance. Once you progress far enough a mixed group (or L3 Bio-soldiers if you don't want the hassle) can take out Intermediate raids with only occasional losses, but by the time you get that far you can replace them pretty quickly.
I do agree that it's not as fulfilling, there should be more equipment that you can unlock to make them invincible with enough time.
Why can't I activate this? I've removed parasites, I have the bottle it needs, and I've unlocked the research. Feels like a waste of money this way
It's an odd bug in the game, you need a Body Modification Factor to be able to click the button, but the odd thing is it removes the Erogenous Zone Factor from your inventory... do it when you have 0 Eros and you can use them infinitly from then on (but I don't know if this has consequences, I loaded after testing).
How to even reduce her resistance....? Its insane high amount and the resource managament is a chaos. Everything is ultra expensive...
Since you've already worked around it I'll post this in case other people want to know.
First step is remove her Tiara and Costume (they total 5 resist per day). The next step is to raise her fear, my favorite is Injection Tentacle or Deepthroat because those both raise her max hp, but another is Electric Torture. It's still a struggle because she loses quite a bit of fear every day, so you'll need health potions to keep her healthy enough to use them often. If you want to keep her Mind value high, you do have to be careful accumulating too much fear though because it will drain quite quickly (especially if you're raising Sorrow as well).
Another tactic is to break her transformation by draining her Mana, many training options have fear added to them and it doesn't drain as quickly. To accomplish this you have a few options, parasites, EN Absorbtion Unit, or Milking device. EN Absorb is straightforward, just get it and use it (the last tech is 40k cash though). For parasistes you'll need at least 3, but since the last 3 are unlocked around the same time may as well go for 4. Milking requires at least 1 level breast growth, Lactation Mod (at least 1 level) and the Milking Device.
Personally I don't like to reduce resistance, because I like her training to last. Once Fallen is maxed out it forces a game over, but I get the impression the dev will change this in the upcomming update.