This ran okay for me on a 1660ti. It's been a couple weeks, since, though - I was probably running at a low (but tolerable) framerate. Turn the fluids settings up too much and it would bog down, though, for sure; but, things were mostly fine, otherwise. Worst case for fluids bogging things down was (especially with settings turned up) if: playing as a male PC, in doggy-style animation (PC is bottom), and PC came, making a puddle under him - to which he keeps adding to, and stirring around with his dick, essentially, lol. Every other animation seemed to handle things fine. Just adding my experience with it. c:
Edit to add: no crashes here, either. I'm not overclocking or running anything crazy.
If running an overclock, it might not be as stable as you think you've set it. Separately, it might be worth checking for memory errors. I recently caught a stick of RAM going bad (for the second time, in this same system...). It finally got my attention when I, too, had some random "GPU crashes." Hope some of this helps!