Before download? Not that I'm aware. However, what you can do is delete mods after you've completed downloading/unzipping. A good place to start might be the mods specifically for studio. The path is [(main folder) > mods]. In that mods folder, there's should be a folder or two with numerous mods specifically for Studio Neo V2. If you're confident you'll never be using studio, you could probably just delete those entirely, they shouldn't affect the main game. I say "could" and "shouldn't" because I've never done it. Do so at your own discretion. Might be wise to back them up before outright deleting them, just in case it breaks the game (I really don't see it doing so, but you can never be too careful).
There are also some character cards, outfits, and studio scene cards which you may or may not be interested in. While these don't take up as much space, if you're never going to use them, you can find them at [(main folder) > UserData > Chara] for character cards (these are like playable characters or female characters you can interact with in game that have been made by other users and included in the Repack), [(main folder) > UserData > Coordinate] for outfits that other users have created and included in the Repack, and [(main folder) > UserData > Studio > Scene] for premade studio scenes. Don't delete the folders themselves, as you need those folders to exist for the game to function, but feel free to pick and choose from these folders and their subsequent subfolders anything you don't see yourself ever using, which will free up more space for you.
As a side note, if you have an external hard drive laying around, like a terabyte, you can throw all of your HS2 files on there and your game should still run just fine, so it's not taking up any space on your actual computer.
it will then be in femdom as Herbmetaru said
