At some point, I'm incapable of completing the strip show because Karryn cums nearly at every round until her HP and Energy are depleted. Am I the only one with that problem?
If you don't do intermissions to hide behind the curtains and take breaks, she'll suffer from more "Sight-based orgasms" that basically chain together until she passes out. To prevent this from happening your options are basically raise your sight resistance as high as you can (See no Evil before stepping out of the Curtains or accessories/titles), or unlock more passives to reduce Bliss chance, cuz Bliss is ultimately what causes fails as they chain together and basically prevent Karryn from doing literally anything besides taking the Breathe action.
Another way to kind of cut your potential losses and still come out with money from the deal is unlock the Private Room and then do the Private Room activation after she starts getting too horny and cumming too much, because with the private rooms, it usually leads to sex, which lets them fill her up with cum and restore her energy, and that gets you money per person that joins her back there.
Just remember to take breaks every 4-5 minutes while she's on stage if you are doing the longer runs (20/24 minutes). A few angry patrons is more worth it than failing altogether and getting the punishment, which results in her getting way more fatigued the following day (and typically left scandalous, which prevents you doing much of ANY activity besides Strip Club and story progress).