The cheats are applied in many different files, depending on what they do. Basically in the functions that calculates how often enemies act there is a line that checks if you're in easy mode and the cheat is active and then changes stuff. So there is no easy way to enable all cheats in non-secretary mode, but you can delete the checks individually.
You'll find the lines easily if you search for
cheat in the following files (the names are pretty clear what cheat is meant):
RemtairyCombat.js: double & triple physical dmg
RemtairyEnemy.js: always act
RemtairyKarryn.js: 1/2 & 1/3 stamina regen, no evasion, half exp
RemtairyMisc.js: double & triple sex dmg
RemtairyPrison.js: -5 & -10 control, instant riots
YEP_X_Autosave.js: disable autosave
Just replace the
Prison.easyMode() part with
true to remove the secretary-difficulty requirement for that particular cheat. (If you have some experience in programming you can make nicer edits, but the outcome is the same)