"but you can't win by just dodging.. you're just like an annoying fly
furthermore UI doesn't last long enough to tire jiren out, especially if he ignores you...
and just like kaioken it takes a toll on the body
especially on a fragile human body"
Factually untrue. Once again, in manga version of Super, Roshi solo'ed a pride trooper on his own, simply by dodging and annoying that other guy so much, and then he guided his opponent's own strength and made him ring out. And once again, Jiren would not simply ignore Roshi and Krillin, because even in the original canon manga story Jiren didn't just ignore Roshi when Roshi charged at him. He started fighting Roshi, and losing his cool. So in a hypothetical second timeline with Roshi and Krillin both stronger than the original timeline after time repeat Krillin knows what's at stake. They do have a chance to win. Not a great, sure fired chance, mind you. But it's not 0% where they can't do anything against Jiren. Seriously, Jiren's mind isn't as perfectly balanced as some people seem to think.
"so there is no way roshi or krillin can beat jiren, they are simply too weak.
earthlings are the weakest race in dbz their bodies can't get much stronger
and again humans can't transform"
Once again, factually untrue. Because earthling were the first to get a transformation in Dragon Ball. It's just not a prominent transformation in the story so most people don't think about it. Yeah. I'm talking about Roshi's power (buffed muscle) stance. You can argue it's technique, but then UI should also be categorized under technique/skill than a transformation. And Roshi's power stance physically changes one's appearance/build more than UI, which means earthling's body is capable of some kind of transformation.
"goku/vegeta can get stronger because of saiyan dna and this dna has no limits
i mean seriously saiyan bodies get stronger from fatal injuries
and kogu died like 4 times already"
This is point, I half agree with. I would say Saiyan body does have the advantage on how fast it can grow stronger compared to an earthling, which would obviously give them a higher power ceiling. But as far as I can tell (granted, I haven't been following Super manga, since I don't think it's very well written), there's no hard evidence in DB lore saying earthling's body has a hard limit on how much power it can hold. The fact Super brought the earthlings back as fighters, and have them fight in universe survival tournament rather than dig up... I don't know. Namekians (who with their regeneration ability, suggest their body should be more suited for fighting than earthling), or other dead fighters like Freeza, suggest otherwise.
"humans can only overcome their limits through genetic engineering
by pumping their bodies full of super steroids
by becoming/being born a mutant/hybrid
by replacing their weak body parts with machines and turning into androids/cyborgs
by being possessed by demons/spirits or alien parasites
by some kind of magic...
by hybridization/crossbreeding with more powerful races like saiyan or viltrumite... "
This point, I once again half agree with. The fastest way for an earthling to break their limit is through some kind of genetic/cybernetic ascension in DB. But I don't see it as a bad thing. If anything, resourcefulness is the strength of earthling in DB compared to Saiyan's brutal strength. Gero kidnapped two street punks, and after some cybernamic enhancement, knocked the super out of the super saiyans. One said street punk, who had no systematic training, and after fighting off some space poachers/big game hunters, was able to fight side by side with literal god mode Saiyans in universe survival tournament (granted, this is one of Super's big bad/lazy writing moment). And considering most earthling are naturally at around battle power of 5-10 range, saying earthling 'can't overcome their limit' is flat out disgenuine, since even if we low ball the earthling Z fighters battle power by Super era, they would at least be over Goku and Freeza's final battle power during Namekian storyline. That's a pretty astronomical 'limit break' if you crunch in the numbers. And they did it through pure training, with no easy transformation boost, or natural power growth just by getting beaten up.
So once again, I simply don't agree with the whole earthling shaming among certain DB fandom. Earthling characters don't get love from Toriyama and the extended DB production team because they aren't as popular as the fancier alien characters. But I always seen earthling more capable at breaking their natural limit compared to the alien races from a pure proportional level when they don't have Namekian's regeneration, Saiyan's growth boost, or Freeza race's inherent strength.