All the girls at the same time is recommended, especially since some character events are required for main and other character events outside the character that event is for.Thanks for the info... That's scary. I guess I'll work on all the girls at the same time then. Or does that not help? This is actually bugging me. I want a perfect playthrough without spoilers. Does the game tell you this? Or is it something you figure out yourself later on. I'm thinking of 2 girls that this possibly applies to right now.
The text does warn you within the context of the game world, so if it specifically mentions things that are common sense in the real world when given the information beforehand or it outright says don't do something, heed that warning.
Also, definitely pay close attention to every single detail in every event. This game is being specifically designed to make a perfect playthrough difficult if not impossible, but it seems more than one of us is trying to beat those odds. I'm glad I'm not alone.