Some food for thought
During Ami's delirium in
Della, she said something that doesn't simply come from trapping in bedtime story hallucination and/or a fit of anger.
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Why haven't you kept playing BREED YOUR NIECE MINI GAME?!?!?!
Ami has always been a prime suspect of time fuckery-related matters or basically anything unexplainable, but it also has always been hard to really tell how much she knows and/or how much she's involved. This time, however, these lines aren't delivered during resets, happy events, or dreamy sequences to confuse or shock players; she delivers these words diegetically to Sensei.
So, does she in fact know A LOT MORE than she lets on? Does she also know about the reincarnation, but have an opinion on the complete opposite side of Maya?
Or, Is Ami during
Della in a god-induced blackout and something other than Ami was scolding us through Ami?
Or, since Ami recites parts of conversation she and Sensei had back in
A New You, perhaps after finding out "his brain being stupid" and how similar the situation was compared to a manga or a game, Ami from that point forward started treating things really like a game (a porn game no less) and wished Sensei to do the same so that her envisioned future of being with her uncle is no longer impossible?
Personally, I think Ami subjectively wanting Sensei to treat this like a game so that she has a chance to end with him is the most straightforward take. But things are a lot spicier, much more interesting, and still explainable if she really knows more. Especially, I think getting Ami pregnant "should" have some otherworldly effects solely because events like
Am I Awake exist, as if that event foreshadows what "her epilogue" looks like, or perhaps foreshadows how all the other Senseis who immediately slept with Ami ended.