Ayane and Noriko both have a very strong but different 'need' for Sensei. For Ayane its a powerful need for a male figure in her life to help take care of her. For Noriko, its possible her feelings for Sensei are genuine if you can dig past the obsessive, almost manic need for him in her life after he vanished from her life years back. Neither of them would deal well with finding out they're not the only interests Sensei has.
Ayane would be seriously hurt (again, fuck you Kirin) but would never be willing to give him up, not after caring about him for so long.
Noriko.....she's got a big talk about anyone trying to hook up with Senei in any romantic way, but i'm not entirely convinced she'll follow through. So far she's been a super heavy flirt but she kinda crumbles when things start getting more seirous. The only thing that has me on the fence about her still is Maya's explosion during Noriko's introduction in class.
As for Makoto, i think she's got a better handle on herself after Bluejay, or at least a better understanding of the 'relationship' between her and Sensei.
Chika.......yeah, she won't handle that well at all. The only possible bright side is Sensei (seems to at least) genuinely care about her, more so than most of the other girls, on a level with Ami, Ayane and Rin IMO.
AAHHHHH this game makes my brain hurt
Also, HUGS FOR MAYA!!!!!