Rin pretty much offered to have sexual interactions with him with her wrist torn open, I can't see it ever being as uncomfortable as Io's stomachache. At most I think Rin'd be like "yeah, maybe that was a mistake" later, and move on.
Also, I mean, Makoto raped Akira during a depressive episode and I think a Rin sexual/depressive episode would mirror more of that than Io's.
I'm not sure about Yasu, but I also have a little difficulty seeing her in a traumatic sexual event without first having some character development that pushes her a little far from supernatural stuff. Otherwise, I'd be half-expecting her to not even remember it/assume it was god's command or something (like what already happened).