Actually there are only a few specific situations which, to me, would be really anxiety inducing and therefore really NTR.
And those situations I avoid like the plague.
And if those situations turn out to be actually unavoidable, that's when I will rage quit a game.
Fortunately this is quite a rare occurence.
This seems to me the sanest approach possible: simply stop playing a game whose themes you don't vibe with. And also very important: I think nobody should take any of those themes as a personal attack - there are very few media pieces that are genuinely meant as "rage bait", and all the other ones shouldn't be treated as such.
Finally, and this is also important: people should learn how to distance themselves from the media they consume. Expecting all the authors to categorize their games, or other forms of art, according to an ever-changing landscape of theme definitions and tagging systems is completely unreasonable. As is unreasonable, in my opinion, for any player to feel the need to be shielded from the consequences of their choice to play a game.
My personal opinion is that this kind of approach of removing responsibilities from people willingly approaching a medium has done nothing good, neither to the authors nor the games. We (as players, or movie watchers, or music listeners) had to face hordes of outraged people getting offended because of themes portrayed in our favorite media - mostly from media outsiders, too. What I definitely wouldn't want is the same to happen from people inside the media. What's worse, we're also lowering the tolerance bar: what once was considered offensive, now is considered psychologically damaging. But again: if you're in front of a monitor, and simply reading of a guy getting cheated on is enough to trigger a genuine anxiety attack, I may understand, but won't justify any sentiment that reality should bend to defend you from itself.