get real, town is in the middle of nowhere (not totally literally) and it has no access to sea so yakuza's not interested.
while i agree that a teamup between RMC & the Yakuza is unlikely,it has nothing to do with the location,which is (if im correct) a little bit more In-land then LA(a large coastal city)
Also a Assassin was dissipated after one phonecall so they have a presence in the area,which is also why the Hots spring owner had the contact and Said resort is even more remote then the town.