Well, I don't know how Dev thought of doing it, but in my games of Vampire and Werewolf I have seen more than one fight between a Cliath (the lowest rank of werewolves) and an Ancillae (a vampire of about 200 to 300 years) and things tend to go very badly for vampires. In reality, intelligent gangrel tend to escape as fast as they can and merge with the earth whenever they have the chance. An Assamite or a Brujah armed with a sword has some chance of winning, without a sharp weapon or some silver it's like trying to knock down a mountain with your fists. The rest of the clans are usually not good enough in combat to have any chance in a fight with a Werewolf, unless they have the opportunity to use disciplines that are not expressly designed for combat. I've seen used pressence to temporarily stop the werewolf and have a chance to scape, and some thaumaturgy paths can be remarkably effective in combat (like Creo Ignem, starting at 3rd level you can throw a fireball powerful enough to stop the werewolf, although then you have to escape from the fire you have caused, but a Tremere will always consider that the best way to confront a Werewolf is to have another fight the Werewolf.)
You are talking about the masquerade line of games.
In that line of games werewolves are extremely overpowered and more like a villainous endboss than a somewhat balanced adversary.
In addition vampires are portrayed as relatively squishy and fragile. Even mere humans pose somewhat of a threat.
With this portrayal that series, which includes a Pen&Paper RPG which you are likely referring to, is more or less an outlier and not the "standard" in that regard.
The backstory of Dragomira for instance is that she was a professional werewolf hunter and has singlehandedly wiped out werewolf clans for multiple centuries.
That alone should clue you in that this game is not set in the masquerade world ...
The "Bog Standard" is relatively akin to the portrayal in the underworld movies.
Werewolves and Vampires of comparable rank are relatively close in combat prowess.
Here the MC is of slightly higher than the absolutely lowest rank werewolf since he discovered his gift a few weeks ago i.e. is neither old nor trained enough for higher ranks and dragomira is not necessarily the strongest vampire "alive" but close to the highest rank of vampire.
Honestly not even an earnest competition.
