I couldn't find this mentioned anywhere, but when using the ipatch and clicking on Laura's entry in the characters bio's, I get an exception error because the game can't find /images/x/laura_text_i.png
Other thing, it'd be really nice if there was a toggle to disable the music overlay thing in the top right corner. 99% of the time, I turn off music in games, so that overlay is 100% useless to me. It also tends to pop up if your mouse cursor even thinks about going anywhere near the top right corner.
The option to disable the glossary link text that shows up a ton in the dialogue would be nice too, or at least chance the colour to the same as the rest of the dialogue text so it doesn't scream at me "I AM IMPORTANT! CLICK ME! CLICK ME!!!" every time one shows up. It's not important, and there's already a glossary button on the top left corner. There's a fine line between helpful and pushy, and for me, this one crosses that line. (and unlike the music overlay above, I can't do a simple search/replace to disable it myself).
EDIT: The entries on the stats screen (speed, strength etc) desperately needs a back button. As it is now, it seems that if I want to read up on what, say, 'speed' does, I can't just go back to the stats screen to then look at another stat. Instead, I get pushed back into the game, so I then need to open up the menu, then back into the stats screen. A 'back' button on the speed/strength/int/etc. entries would make this much more usable.