Unfortunately, that threesome won't happen because they are related in the unpatched version, so Patreon would ban me.
Other X-somes that won't happen:
Kiara+Eileen
Samantha+Simone
Debbie+Lisa
(Betty or Meemaw) + Norah
Saira + Kalyani (Student from the last batch)
Betty's scene had 18 animations (in 5 sets) and over 4,150 renders. I hardly will go beyond that for a single scene.
This does raise an interesting question though (and of course it's in jest, because I think the processing power to render the scene, plus the posing, writing, etc. would be too much!)... when we get the inevitable game-ending orgy, how do we decide who will be involved? While all the other girls are getting themselves ready for it, will we have Eileen and Kiara; Norah, Betty, and Meemaw; Samantha and Simone, etc. playing rock, paper, scissors to see who can go in and join them and who has to sit it out?