Depends on your definition of NTR. If you define NTR by "all female npc's belongs to MC and only MC - everything else is NTR" than no, in some cases it is not avoidable. If you define NTR by "MC's gf/finacee/wife banged by other dude, than yes, it is avoidable".
I dislike NTR, and I like that you can choose to avoid it.
On the other hand, I am not a fan of BDSM or domination (male or female) or scenes without the MC. I don't care that it exists in the game if I can skip the scenes (it is not necessary to avoid the scenes, but I prefer if I can avoid them or at least not see them, in fact I will skip the scene anyway). And blackmail and humiliation are things that I don't enjoy and I usually skip scenes that include it (Only if I think the character deserves such behavior would I watch the scene).
I don't know if the game has a lot of this tags (BDSM, domination, humilliation and blackmail), but befor I think to download it, I prefer to know it.