Well, for looks I think that most of them seem to have a kind of weird face. I don't mean that in that they are ugly, or anything, but to me it is something like the uncanny valley. Hard to describe, but you know it when you see it. I would almost say that some of their faces are a bit pudgy feeling, but not overtly. I don't think I am making sense here though. I would say that none of them are what I would call really 'hot'.
All that being said, Marie does it for me in a weird way. Her overall body and facial expressions and personality. She wouldn't be who I would pick out in a lineup at a brothel, but someone I would not be unhappy with as a girlfriend. I guess you could say she is on the ample side of curvy without slipping over into the 'fat' category.
It's funny (but not exactly surprising or new) how tastes vary. I myself find almost all of the women quite beautiful. But I do understand what you mean about the uncanny valley effect. The faces almost seem fluid at times, and almost a tiny bit detached (visually, not physically) from the bodies. Almost, but not really, as if they were created with AI. But maybe they are just realistic enough to simply be living in the uncanny valley and that's what's making it seem slightly weird.
When I started playing I got a strong feeling that I recognized Jenny from somewhere, and after a while I realized that I actually had a boss that looked not entirely unlike her (although not nearly as beautiful) a while ago. She even had almost the same kind of position as Jenny, funnily enough.
I sometimes get the feeling that these characters are based on real people, just because they're not as cartoonish as VN characters usually are.
But I do love the game, the characters are feeling like real people, and the story is intriguing.
I'm at the point where the company has just been closed and they're planning their own studio, and I can say that I wouldn't mind if the game turned into a full-fledged office simulator, because it's so well written. And the posing, particularly the facial expressions, is absolutely fantastic.