One thing I took a long time to discover was how the different girls react to your "alchemical concoction" to reduce their addiction to you. I've not played the addiction route often, and when I did, I was straight with them and told them it was seaman's semen, you know? But when I tried to hide that from them and present it as the result of my many hours of chemistry study, every girl from Emma to Jubes realized it's cum at some point between handing it to them to when they've swallowed it. The general opinion was negative, unless you already had high points with them.
The funny thing comes with Rogue and Kitty. They're virginally oblivious about it and think it's a weird syrup. BUT, after giving you a bj and swallowing your spunk, the next time you give them the potion it downs on them it was da coom from the very beginning. It's a certified bruh moment, let me tell you.