Hey, first let me say I appreciate you playing the game.I do have a few questions / concerns though, Wildman Dev.
Let me answer them in order as best I can.
The freedom of choice is a bit hard to describe - Most girls will have routes and options to choose how you want to deal with them: It kinda depends on the girl when it comes to how their routes will go. Most of these choices will be different sex scenes/normal scenes/dialogue/relationships - but still relationships - at least for most girls. Again, it's tough to accurately describe because it's not the same for all the girls.
As far as strictly saying "no" to a girl permanently, or missing out on her scenes/content altogether - nothing like that is planned. However, in the next update the option to skip sex scenes will be available, so if you really hate a girl or don't want to see the content, that'll be possible.
In this sense, Stranded in Space is a bit more kinetic than some people prefer, which I understand. It'll still have more unique playthrough content/sex scenes/dialogue than any other game ever, which also some people don't seem to like, so shoot me! (Side note: a "see non-activated routes sex scenes option will be available for my Patreons.)
The planned content is missing A FUCKTON, which I'm trying to find in my thread so I can change. I'm shocked I haven't done this yet. Harem/Anal will 100% 100% 100% be in the game, as will so many other fun ones!
Lastly, there will never be any futa/trans stuff in Stranded in Space.