I've never played TLE. Is it worth it? I know one of the characters (Amanda Belcroft or something?)of that is in that love potion subplot, but i really didn't like her look. Puffy cheeks, fat lips, etc...not sure if there are other girls worth playing for
First of all, let's get the name right. It's just "Lust Epidemic". There is no "The" in that name. So the abbreviation is just LE, not TLE.
As for whether the game is worth playing, keep in mind that game started 6.5 years ago, and some of the characters dated back even further with NLT's old comics. In terms of character models and graphics, 6.5 years is pretty much ancient history. So if all you care about are how the visuals, maybe it's not worth it to go back and play it.
But if you value stories, it definitely doesn't hurt to go play it and understand the whole continuity a little more.