I finally got around to playing this in a non-vanilla run, man, frankly the mechanics are a wreck.
There's almost no tools to go in the 'opposite' direction as far as transformations go, yet a cornicopia of events to push you further in the 'non-vanilla' direction.
Like in theory, you're working at this lab chock full of transformation drugs for every application. John or Tasha forcing you on your knees everytime you see them? That should be an easy clandestine medical fix! But no, nearly all those variables set are permanent, with the exception of the one-time tasha reset event. But even that doesn't roll back the pervasive dreams.
I dunno, it just feels very Rocky-Horror-Picture-Show-esque, and that's not a compliment - as in it's fawned over by fans espousing how "zomg it breaks gender norms and is full of fun weirdness!"
Yeah but the weirdness only ever goes in one direction; Straight --> Gay, Dominant --->submissive. There aren't any women who start as strapon-wielding-lesbian-slaves who then become demure belles. Everyone's just fodder to be torn down to the lowest level. And that's completely fine for a pure corruption game! But for a game about transformation drugs, I'd expect more variety in the transformations. If anyone thinks I'm talking nonsense, you need to look at the %chance for each outcome for the dream transformations in the script, and the relative gain/loss amounts for different activities.