Imagine the game with male protagonist where he explores entire LoL world meeting all characters as an adventurer of sorts, quests, unique story lines(heck protagonist could be even future champion or something if it was done neatly intertwinning with other character stories) with top notch art, minigames, heck it could even be made with rpg maker imho, if art was nice and level design too but oh well, I guess it sounds like too much quality for amateur game developers.
And it would be really popular too, there isn't a single fully fledged lol themed game like this, and LoL obviously still is popular, but I imagine lol porn could be even more popular heh