Is there a guide somewhere to play optimally or is it just best to play as a man?
Do whatever gets your dick hard/pussy wet.
It's a text-based erotic rpg my guy, loosen up and mingle with the locals.
But a few tips:
-Don't pick up strange eggs in the ground.
-Equip according to your class. I usually go Tech Specialist and most of their abilities require Energy Weapons to trigger. But other classes are more adept at using classic ballistic guns or eschew guns at all.
-In addition to this pay attention to damage types. You might've noticed that Cunt Snakes are hard to kill using ranged weapons but easy to kill with melee attacks. There's always a flag of what damage your weapon does in your inventory.
-Sleeping in your tent is the fastest way to heal and regain energy. Only bother with healing items like the Mhen'ga Mango or Health Kits if you're low on health during combat.
Also there's a wiki
You must be registered to see the links
. It's not totally up to date but it'll help you right up at least until Dhaal.