Yes I am planning to add a(n optional) more full fledged progression system with what you're willing / unwilling to do at some point, at the moment it is probably way too permissive.
Gating is one way to make masc/femininity actually feel meaningful.
An even better way, although this could be a big change, would be mechanical.
For example, instead of pills that instantly take effect and last for a specific amount of time, you could have something like pills that take effect when "potency" > masculinity, where potency decreases over time, and reverts when "potency" < masculinity. (plus, perhaps, some roll). And perhaps "losers" are easier to transform. Could be based partially on fitness.
Eg. The "more of a male" someone is, the more difficult they are to transform, and the shorter the length of the transformation.
Which would play into the whole "power dynamics" aspect, and adds a lot of narrative space. For example, the whole "Bruce rivalry" could be less a series of "one shot" and a more persistent and drawn out struggle.
Here's another idea that could be used in conjunction or by itself:
Split at least the charisma and strength stats between male and female, at least partially.
Since "desirability" seems to be derived from a mixture of fitness and charisma, you get this tight coupling of "desirable male" to "desirable female," and you don't really get "desirable female vs loser male" or vice-versa.
There are tons of ways you could go about this, but off the top of my head I'm thinking of half of your charisma/fitness stat being "general" and the other half being "sex specific," where you gain a bonus to the "sex specific" stat XP based on masc/femininity, and also decay when in the opposite body based on masc/femininity.
