To be fair, the nemesis she's up against (Kendra the Puppetmaster) is quite literally insane. She's done an excellent job of framing David, but her tools are completely untrustworthy and she's trying to enforce loyalty via a gun to the head. At some point her plans are guaranteed to come crashing down, but we don't know if that'll come too late to save Anna's marriage.
A break-up seems to be inevitable at this stage, but a reconciliation might be possible after the truth comes out. Anna will be a very different person by then and David may see her actions as unforgivable, even if she was tricked into them. A more likely outcome is that David leaves her, Kendra goes into the nut house and Anna has to surrender her dignity to Hank in order to get that promotion and support the baby. Leonard, Robinson and Chris will screw each other over, Marvin will go to jail and Jake will
still be trying to get into Anna's panties. Stromberger will hopefully die of heart failure after too much fantasising over Anna.