I'm afraid that a happy ending with Bella and MC walking off in the sunset together, hand in hand, is very unlikely after that ominous glimpse into the future ("real reason behind her tears", "calling out for help" and so on). I have a sense of impending, inevitable doom now and Isabella's right in the center of it. Which sucks because she's my favourite.
If it turns out that she has serious mental health issues, and game seems to suggest it, then I don't see chance for satisfying resolution. I might be wrong, of course. God damn, I'd like to be wrong. Let me know what you think, guys!