The problem is that her backstory and connection with Jaye and Alex was so good here that in the next game it either feels like her settling, or in their pursuit of making her new relationship even more epic they run the risk of belittling, or diminishing the relationship that got the fanbase to fall in love with her in the first place. Lets not forget that what she does in this game is no small feat, she loves Jaye and at least had a crush on Alex for 15+ years, she was their firsts, but they were also hers firsts and she sacrifices her feelings for both and goes out of her way to play matchmaker and wingman for them for 5+ years. How do you top that in a new story? How do you make her moving on not feel like her settling for the second best option, since she couldn't have this one? There are so many things that have to be carefully considered that it seems like an impossible mountain to climb in terms of writing. New game also has way more LIs, so even harder to find screen time to build meaningful relationships with everyone...
People love the idea because they think of it only on the surface, but the more you analyze the possibilities you realize that lighting in a bottle should be left alone. Sequels are most of the times worse for a reason, sometimes despite best intentions and double the effort.
I want to be proven wrong on this one soo bad, I guess we will have to wait and see, right not even if I focus on the present I see only downsides, no Lisa ending, possibly no Lisa sex scene going forward(I think Stoya more than implied that she will get one next episode, but that was also before they announced the next game, depending when every detail of that was in the plans he might have changed his mind, Jill in DIK was also last minute addition, maybe Lisa was like that), no Jaye & Tara threesome, no Jaye & Tara throuple ending. No matter how slim the chances for those occurrences were before, now they are zero *sigh*