I've always used it without problems. Just need enough iterations. The higher the resolution and quality you want, the more iterations you will need. I set the denoiser to only denoise the final iteration.
I currently have an RTX3060 12G version which is nice (more VRAM is vital), but I used to use a 1050TI with only 4G of VRAM on it and denoising was even more important as that card was not the fastest to render with, but I got some nice renders out of it at lower iterations with the denoiser. But whatever works for you.
I just got done rendering this image using those settings. It will turn out like this no matter what you use, the only difference will be how long it takes (which at 400 iterations, or even as low as 200, is perfectly fine)...
"Carl takes his friend's grand daughter, Wanda, on an RV trip..."
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