Considering that one of the servers that we'll be visiting is likely Andromeda (based on the batch of sneaks preceding the latest one), it's likely that the choices we've made back in 0.4 and 0.6 (iirc one of the survivors in the Collector whodunit said to look for them in Andromeda) are going to affect whatever happens there.
But other than the choice of survivor in the Collector whodunit, the Ekabar choice likely affecting the Great Hunt event, and the Amulet of Blair and Polyjuice being Chekov's guns that will fire later on, there's not much branching path that's likely going to affect the outcome of the main narrative (other than the Amulet tho that's more of a bad ending waiting to happen) nor something that can't be solved by mere change of dialogue or a few differing renders.
Of course, that might change in this upcoming update, especially if said update is going to lean heavily into advancing the main story in a big way and provide branching choices and such.