Yes, I don't know how you missed the skip button when you first play your uncle.. it gives you the choice before you start playing him...but even if you play him, you will still lose, it's rigged for story purposes.... AFTER that first time though, you DON'T need to play him again to continue the story, playing him after that is just extra content/money. The story doesn't revolve over whether you win a card game or not. As for money, you an make money by working on your computer. BTW, if you don;t have enough money to pay back the mob, he makes you work at the gym selling drugs... it doesn't end the game or give you a bad ending. The story revolves more around choices, not money....