Yes you can, just go to "C:user/***name of said user***/AppData/Roaming/Renpy/Harem Hotel-**********" (*** being numbers), and save your file on an other drive than your computer.Can't I just back up save files somewhere else to avoid any risk to them when trying the beta? Or am I missing something?
In a fact, you should back up all your of the folder "Renpy" on an other driver just in case of a probleme with your computer, that way, you can reinstall all your saves or if you did like i did and corrupted your saved file with a beta version, you can re-use your backup file.
It a good habit to make backups and backups of your importants files like saves of porn game and maybe, just maybe your photos.