It's a bug that can happen when you click the back button in the bottom left corner of the screen and get taken to Residential District regardless of where you were a moment earlier, potentially breaking events. You become unable to use Esc to bring up the menu or make manual saves. The only solution I've found is ending the game and loading a save to a point before the bug happens, then being mindful to always rollback the instant the back button transports you to the Residential District.
EDIT: Updated to include the solution. Go to Your Computer in Your Room, then click the power button. This restores the ability to use Esc regardless of how you may have lost the ability to use Esc.
	
		
			
		
		
	
								EDIT: Updated to include the solution. Go to Your Computer in Your Room, then click the power button. This restores the ability to use Esc regardless of how you may have lost the ability to use Esc.
								
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