What does your slut level do anyway? Does it increase arousal damage when using sex skills?
Don't take my word for it, but I believe slut level doesn't do much on its own. (You gain 1 slut level for every passive you get)
its the passives that'll contribute to sex skills via what each individual passive bonus/nerf it gives you. If anything I believe slut level hinders Karryn because it lowers her charm. (I can't remember the exact ratio)
Random passive example: receiving anal creampies restores Karryns energy based on amount of cum, so combining that with other passives which increase ejaculation amount will give extra energy, thus keeping you in the fight longer.
You would be surprised(or not) how many times I have been able to swing a clutch victory because I was able to control internal ejaculation and get enough energy to not pass out and end up in solitary (not that that's a bad thing sometimes
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Which means it depends on HOW your raise your slut skill.
Personally in my playthroughs its good to try and have a fallback sex skill for once you are found in a position that you can't fight to win (for me its always the 3rd floor boss 2/2 wave).
By keeping desires down in some sex skills, you can game/rng the enemy to target the area you want, thus focusing the slut level gain/passives that you get.
Important to keep an eye on it early-mid game so you don't lose control.
Especially debatably important to keep slut levels down to a minimum until you have all floors subjugated that you can for the best possible reward from your NTR king (20 slut level per floor gives best(?) choiced rewards) AND until you get your side jobs set up.
P.S: I'd avoid engaging in the side jobs sexual aspects if you can while you are clearing because it takes fatigue and you may find yourself with such nasty passives (Doubling pleasure gains during side jobs is a ruffy one)
Sorry if I missed anything or this was unhelpful/already covered
Edit
For a full corrupted route do I need to lose all the time or use sex skills in the battle every time?
It's really up to you, you can go a full corrupt route by winning every battle. It depends on how you factor in all your stats and upgrades.
Example: Clear the first floor, getting the bar, and end up getting naively drunk.
Its hard to "clear" the game if you have the mindset of just being a doormat like in other games.(take exhausting drug, get battle raped, move on)
depending on your starting sensitivities, it'll help your corrupt route whilst also making progress.
As others have said, use your sex skills as they get more passives as you use them, such as cock stare/cock petting.
If you end up not paying attention to your gains, you may spiral out of control and not be able to win anything and will shoehorn yourself into a bad end 1.
I personally think its the best way to play as an initial naive warden so you can clear some content and get a solid grasp on order/control/upgrades/income/controlled passive gain.
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I apologies if this has been asked before, but is there a way to increase how often enemies speak and is it possible to change what they and Karryn says? If it has been posted on how to do this I would appreciate know what page.
Only way I know without editing files is to have your desires balanced so it locks out the moves that you don't want, and enables the moves you do want.
Having horny/flustered enemies helps as well so they are less likely to attack and more likely to talk/jerk off