I want to preface this constructive criticism by saying one thing. This is legitimately one of my favorite adult games. With that said, it definitely still has some issues. First of all, you can do the whole NPCs respect orientation thing and still have scenes pop up that go against your character's orientation. I was playing with a female character who likes Trans women and cys women but not men. Then the debauched house party loaded and she was dared to do something sexual with a guy. She was also offered money to shoot a porn scene with guys. And the whole barbecue event with immigrants loaded and randomly had a guy in it. So, quite a few scenes there that don't respect your character's orientation.
It's also odd that the inter-racial kink stuff frequently involves characters who don't look the race they're supposed to be. I have encountered so many characters who are introduced as white but look asian/black/middle-eastern or are introduced as black but look super pale and about as white as they come.
I also think that the game really needs the ability to remove a particular gender completely. If I play Influencing or Degrees of Lewdity, for example, I can set things up so that I'll never under any circumstances encounter a man but in Lifeplay I can put male spawn rates as low as possible but they'll still show up. And yes, I realize that having zero men is unrealistic but this is a game with orcs, elves, catpeople and vampires. It's also a game where people will stop you for sex every five minutes and where you can set it so that there are zero straight people in the town. There is no realism only escapism and I, for one, would very much find it more enjoyable to not have men running around.
I will also pre-emptively apologize if these aspects have been brought up elsewhere. I, admittedly, did not read through the entire 600+ pages of posts to see if someone else had also taken issue with those aspects of the game.