Imma try to be serious for a couple of minutes.
I don't think killing her would be something positive for the game. It would help keeping the forum clean, but it wouldn't be healthy for the actual game.
The photographer's death was fine because was essentially a meme, the death of a hated character by another memeish character.
Killing Nikki? That would completely change the feel of the game, from something positive and fun to a more gloomy and dark vibe. Since even if you hate the character, obviously Tales would be devastated by it. It would affect him, Jess and Molly in a way that it wouldn't feel natural to see them hooking up or advancing their relationships.
From a player's perspective, there are multiple examples of how the playerbase react to the death of a main or a liked character, so again, I don't think it would be a good idea.
But since I like how Sumodeine is handling the story and characters, I'm sure that whatever he has in store, even if it's Nikki's death, he'll know how to properly implement it without killing the lighthearted/fun feel of the game.